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Clean 21: 21 Day Detox

Our Signature 21-Day Full-Body Reset

Inspiring over 200,000 health journeys

521 reviews

$475.00

Clean 21 is a whole-body health transformation program. M.D. designed to reset and restore your body’s natural state of functional balance starting at the core: the gut.

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Complementary products

Clean 7 detox kit including wellness tea, supplements, cleanse shake mix, and latte powder.

Clean 7: 7 Day Detox

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DESCRIPTION

More connected to your mind and body. More grounded in your everyday life.

Throughout the 21-day detox journey to healing your body, you’ll start to notice a positive mindset and create uplifting habits. Nourish with a daily protocol of nutrient dense smoothies, supplements, and whole-food meals following Clean 21 guidelines. On the inside, your body is skillfully redirecting energy and nutrition to boost detoxification and metabolic functions, reduce inflammation, and promote gut repair at the cellular level.

The reset isn’t just felt inside your gut; it sparks a complete mental and emotional transformation, helping you reach your goals and achieve lasting, life-changing results.

Learn more about the 21-day experience here.

Powerful Benefits

Helps reduce inflammation, bloating, and excess weight†
Promotes clearer, healthier skin†
Supports energy, mood, and mental focus†
Supports better sleep, rest, and recovery†
Promotes healthy aging and longevity†

Product Features

NEW Cleanse Shakes: Improved taste to complement any smoothie or liquid base (now stevia-free!)
NEW Plant-based Protein: A high-absorption blend of seven proteins designed to support cellular repair.
High-Potency Probiotics: 10B CFUs and 4-strains for gut microbiome diversity and immunity.
Powerful Supplements: Promote detoxification and gut-repair with just 4 capsules in the morning and evening.
Energizing Hydration Powder: A refreshing lemonade flavored boost of 19 essential vitamins and minerals.
Personalized support: Tailored guidance from a Clean Certified health coach to personalize your reset.
Digital Program Guide: Step-by-step instructions for preparation, your 21-day reset, and post-cleanse weeks; plus Clean recipes.

WHY IT WORKS

When your gut health is off, your whole body and mind feel rough. Your gut holds the key to functional balance. It is responsible for detoxification, metabolism, mood, energy and so much more.Clean 21 works to restore balance by starting in the gut. Remove toxins from processed and inflammatory foods. Restore your health with enriching whole foods, periods of digestive rest, and science-backed supplemental nutrition. Each day, you will safely and skillfully promote detoxification and gut repair to heal your body from the inside out.In 21 days, you’ll reshape your cravings, revitalize your mind and body, and seamlessly embed new habits into your daily routine. Make Clean 21 a foundation in your health journey, and incorporate a cascade of lasting positive results each time.

HOW IT WORKS: THE PROTOCOL

Your Daily Protocol: Each day during your 21-day reset, you'll enjoy smoothies, a whole food lunch, and supplemental nutrition to promote detoxification and gut-repair.

Morning: Hydrate Powder Mix with 8oz of water
Breakfast: Smoothie with 1 Clean 21 Nutritional Mix + Take 1 Supplement Packet.
Lunch: Whole Food Meal + 2 Digestive Enzymes.
Dinner: Smoothie (or soup) with Clean 21 Nutritional Mix + Take 1 Supplement Packet.

The Clean 21 Elimination Diet guides on what to eat and avoid. Temporarily cut top inflammatory culprits like dairy, refined sugars, alcohol, gluten, and coffee; and enjoy an array of colorful, nutrient-rich foods. It’s easy and flexible—no calorie counting and no scales.

Digestive Rest: Each day includes a 12-hour eating window and a 12-hour overnight fast. You'll start and end your day with a smoothie to ease digestion and help your body focus on healing.

Supplemental Nutrition: Boost detoxification and gut repair with Clean 21’s unique blend of science-backed supplements.

Commitment to Self-Love: Use this healing journey to set intentions, practice mindfulness and movement, and discover what works best for you to create a holistic experience.

WHAT'S INCLUDED

What’s in the kit:

42 Cleanse Shake nutritional mixes with plant protein and immunity-boosting probiotics
42 supplement packets (CoQ10+Magnesium blend, Milk Thistle, and Glutathione)
21 daily servings of digestive enzymes
21 hydration powder sticks

Each program comes with a Digital Program Guide, complete with step-by-step instructions and recipes, and 1-1 Health Coaching support.

INGREDIENTS

Our Clean 21 kit ingredients are:

USDA Organic (Cleanse Shakes)
Non-GMO
Stevia-free
Premium quality, functional ingredients (no fillers or additives)
Vegan
Top 8 allergen-free
Free of gluten, dairy, nuts, and soy
Stevia-free

Read the nutrition labels here

Cleanse Shake - Vanilla

Fermented Organic Protein Blend: Organic fermented pea seed protein (Pisum sativum), Organic fermented brown rice seed protein (Oryza sativa), Organic hemp seed (Cannabis sativa), Organic pumpkin fruit (Cucurbita pepo), Organic flaxseed (Linum usitatissimum), Organic mung bean (Vigna radiata), Organic green bean (Phaseolus vulgaris)

Probiotic Blend: Bifidobacterium bifidum, Lactobacillus acidophilus, Bifidobacterium longum, Bacillus coagulans

Other ingredients: Organic Natural Vanilla Flavor, Organic Monk Fruit Extract

Cleanse Shake - Chocolate

Fermented Organic Protein Blend: Organic fermented pea seed protein (Pisum sativum), Organic fermented brown rice seed protein (Oryza sativa), Organic hemp seed (Cannabis sativa), Organic pumpkin fruit (Cucurbita pepo), Organic flaxseed (Linum usitatissimum), Organic mung bean (Vigna radiata), Organic green bean (Phaseolus vulgaris)

Probiotic Blend: Bifidobacterium bifidum, Lactobacillus acidophilus, Bifidobacterium longum, Bacillus coagulans

Other ingredients: Organic Fermented Cocoa Powder, Organic Flavors, Organic Monk Fruit Extract.

Cleanse Shake - Plain

Fermented Organic Protein Blend: Organic fermented pea seed protein (Pisum sativum), Organic fermented brown rice seed protein (Oryza sativa), Organic hemp seed (Cannabis sativa), Organic pumpkin fruit (Cucurbita pepo), Organic flaxseed (Linum usitatissimum), Organic mung bean (Vigna radiata), Organic green bean (Phaseolus vulgaris)

Probiotic Blend: Bifidobacterium bifidum, Lactobacillus acidophilus, Bifidobacterium longum, Bacillus coagulans

Supplement Packets

Milk thistle (seed) Extract (Silybum marianum)
Other ingredients: Modified Cellulose, Vegetable Stearates, Silicon Dioxide

L-Glutathione
Other ingredients: Modified Cellulose, Calcium Stearate, Silicon Dioxide

Magnesium (as magnesium oxide, magnesium citrate, magnesium glycinate, and magnesium malate), Coenzyme Q-10
Other ingredients: Rice Flour, Hypromellose, Magnesium Stearate

Hydrate

Vitamin A (beta-carotene), Vitamin C (ascorbic acid), Vitamin D (Vitashine ™ as cholecalciferol), Vitamin K (phytonadione), Thiamine (thiamine hydrochloride), Riboflavin (vitamin B2), Niacin (niacinamide), Pyridoxine hydrochloride, Folate (Quatrefolic ®), Vitamin B12 (methylcobalamin), Biotin, Pantothenic acid (d-calcium pantothenate), Calcium (calcium carbonate), Magnesium (magnesium citrate), Zinc (zinc citrate), Selenium (selenium rice amino acid chelate), Copper (copper citrate), Chromium (chromium chloride), Potassium (tripotassium citrate).

Other ingredients: Citric Acid, Natural Flavors, Monk Fruit Extract, Silicon Dioxide, Beta-Carotene (Natural Color)

Digestive Enzymes

Proprietary Complete Enzyme Blend.

Other ingredients: Microcrystalline Cellulose, Hypromellose (Veggie capsule), Medium Chain Triglycerides

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Clean 21: 21 Day Detox Vanilla

Experience transformative, joyful health

Your journey to long-lasting health begins here. Clean 21 supports your body’s digestive, detox, metabolic, immune, and nervous system functions at their core — your gut. Experience transformative, joyful health with this 21-day full body reset program created by gut health expert, Dr. Alejandro Junger.

More powerful than any detox or meal plan, Clean 21 is a doctor-designed, highly effective full-body transformation. Through this mult-week regimen, you’ll redirect your body’s energy and nutritional resources to help repair your gut, detoxify, and boost metabolic functions, allowing your body to fully rejuvenate and restore functional balance.

Enjoy an easy-to-follow daily protocol features Clean organic nutritional shakes, targeted supplements, and whole-food eating guidelines designed to heal and empower you with lasting health habits. Temporarily bid farewell to common inflammatory culprits like dairy, refined sugars, alcohol, gluten, and coffee, and embrace an endless variety of colorful, nutrient-rich foods in alignment with Clean 21 guidelines. Clean 21 promises profound results and an unparalleled experience in your journey towards lasting vibrant health. Your journey to lifelong wellness begins here.

Key Features

NEW gut-friendly Cleanse Shakes with improved flavor and fermented protein blend of seven plant sources for increased bioavailability and nutrient absorption (now stevia-free!)
Increased-potency probiotics: Now 10B CFUs and 4-strains for gut microbiome diversity
More powerful daily supplements that require fewer capsules (8 total capsules a day vs. the previous 24)
Improved smooth lemonade flavor in hydration sticks for energy and daily dose of vitamins and minerals

Discover the joy of feeling good.

The Clean Blog

Superblend shake in a glass jar with a yellow striped straw.

A Day On The Cleanse

As people get started on Clean, the most pressing question is: “What do I eat?” We’ve put together a sample One Day Meal Plan as a way to show you what a day of eating on the Cleanse could look like. Feel free to customize this meal plan for your...

Supporting Core Functions

Our bodies are naturally going through the processes of detoxification, metabolization, and expelling of toxins all the time. At Clean, we address the body's needs holistically using natural Ayurvedic

principles, promoting wellness from within. We have developed solutions to boost and nourish each of the 7 Systems that conform the integral wellbeing of our bodies.

ENERGY

DEFENSE

STRUCTURE

LEARN MORE

Frequently asked, all answered.

Who is the Clean 21 Reset for?

If you are feeling low-energy, experiencing inflammation, digestive discomfort, having trouble sleeping, or simply feel it’s time for a reset, Clean 21 is here for you. Over the course of 21-days Clean 21 will support your gut healing process, enhance detoxification and help restore your body’s essential functions to a more optimal state.

If you are currently on prescription medication, or working with a health condition, we recommend reading our Health Disclaimer page and consulting with your doctor before getting started. Our programs are formulated only for those who are over 18 years old, and are not suitable for those who are pregnant or nursing.

What is the difference between Clean 21 and Clean 7?

Both Clean reset programs are built upon a MD-designed protocol, as well as shakes and supplements, to tap into and enhance the body's natural ability to heal.

Clean 21 is our signature reset program. If you haven't embarked on one of our reset programs with us before, it's the perfect place to start. You can expect to eat from the specified Clean Diet, observe a 12-hour fasting window each evening, and follow a daily protocol of a shake for breakfast, a solid meal for lunch, and a dinner shake or liquid meal. This program is designed to work deeply and thoroughly over this prolonged, three-week period building on healthy habits along the way!

Clean 7 introduces principles from Ayurveda, and extends the intermittent fasting windows used in Clean 21. This program is designed to achieve a powerful and deep reset in a short amount of time.

Clean offers complimentary health and wellness coaching around both reset programs to further personalize your program to your specific needs and health goals, and support you on your wellness journey.

How often should I do one of your reset programs?

We recommend completing a Clean 21 program 1-2 times per year, and incorporating either Clean 7 or Clean 21 seasonally to revitalize, however whatever cadence you choose will provide strong benefits.

Between resets, you may choose to incorporate some of the principles from your reset into everyday life such as incorporating Daily Shake at mealtime, adhering to the 12-hour fasting window, eating your largest meal at lunchtime, or following a modified cleanse-diet.

What is the 12-hr window?

When the body is constantly in a state of digestion, it doesn't allow for deeper detoxification to occur. After your evening shake, leave a twelve-hour window before having your morning shake. If you have your evening shake at 7pm, you should have your morning shake at 7am or later. The body sends the signal to go into deep detox mode approximately eight hours after your last meal. Then the body needs another four hours to do a deep clean. Eight hours (for digestion) + four hours (for a deep clean) = the 12-hour window. Although you may find it challenging, committing to it will help you get the most out of your reset program.

Are Clean 21 and Clean 7 vegan?

Yes! Both of our reset programs are fully plant-based and vegan-friendly.

Are Clean 21 and Clean 7 organic?

The Cleanse Shakes in both of our programs are USDA certified organic. In Clean 7, you will also enjoy USDA organic herbal supplements and Tulsi Wellness tea.

Can the Clean Program Diet accommodate Paleo, Keto, or other dietary preferences?

Clean Program Elimination Diet guidelines can easily accommodate a vegan or non-vegan diet, meeting your unique dietary needs. Whether you are plant-based or pescatarian, Keto or Paleo the diet is inclusive of an array of eating styles and can always be modified with the support of our Clean Wellness Coaches.

What Can I Eat on Clean 21 and Clean 7?

Throughout the Clean programs, the goal is to avoid major allergens and inflammation-causing foods, while focusing on delicious and nourishing whole foods including fruits, vegetables, grains, proteins (chicken, turkey, salmon, nuts and legumes for example), and superfoods. Clean provides you with an elimination guide and a robust list of foods to choose from to add to your shakes and to prepare satiating meals to compliment your program.

Can I do Clean 21 and Clean 7 back to back?

Following one protocol with the other will enhance and deepen results. There is no preferred order, feel free to begin with whichever you choose!

When should I call a Clean Health Coach?

Clean Health Coaches can help you stay on track during your cleanse, answer any questions you may have, and help you develop a post-program plan. You can book your one-on-one phone appointment before, during, or after your program!

We also offer support by phone and email, so regardless of what your routine is, you can get an answer to your question quickly. Please note at this time coaching calls are only available to our US and Canadian customers.

Do the kits require refrigeration?

No, the kits are shelf-stable and do not require refrigeration.

"After doing the cleanse, I have been able to make better choices with my meals and really listen to my body when it is hungry. Before the cleanse, I struggled to get my weight down and control my eating. Now I am eating to live instead of living to eat. I feel lighter and so much better."